What is a neuroendocrine tumor of the pancreas?
A neuroendocrine tumor (NET) of the pancreas is a rare kind of tumor that starts in the hormone-making cells of the pancreas. Some of these tumors grow slowly, while others can grow fast and spread.Causes of neuroendocrine tumor of the pancreas
These tumors form when hormone-making cells in the pancreas grow the wrong way. The exact cause is not always known.
- Changes in the DNA of pancreatic cells
- Certain inherited conditions
- Hormone problems in the pancreas
Risk factors for neuroendocrine tumor of the pancreas
Some things can make it more likely to get a pancreatic NET.
- Family history of MEN1 or other gene syndromes
- Being over age 40
- Having diabetes or other hormone problems
- A history of tumors in the stomach or intestines
Symptoms of neuroendocrine tumor of the pancreas
Some NETs cause symptoms by making too many hormones. Others may not show signs until they grow larger.
- Belly pain or a lump you can feel
- Diarrhea or stomach cramps
- Weight loss without trying
- Skin flushing or feeling hot
- Blood sugar changes (too high or too low)
Diagnosing neuroendocrine tumor of the pancreas
Doctors do tests to find out if you have a tumor and what kind it is.
- Blood or urine tests to look for hormone levels
- CT scan or MRI to see the pancreas
- PET scan to find out if the tumor has spread
- Biopsy to study the cells under a microscope
Treatment of neuroendocrine tumor of the pancreas
Treatment depends on the size of the tumor and if it has spread.
- Surgery to remove the tumor
- Medicine to control hormone levels
- Targeted therapy to slow tumor growth
- Chemotherapy or radiation for more serious cases
When to Seek Care
Call your doctor if you have:
- Ongoing belly pain or cramps
- Fast weight loss
- Changes in blood sugar
- Skin flushing or new hormone symptoms
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