What is mesothelioma?
Mesothelioma is a rare and aggressive form of cancer that develops in the lining of certain organs, most commonly the lungs (pleura). It’s most often caused by exposure to asbestos, a material once widely used in construction and manufacturing. Mesothelioma can take years—sometimes decades—to develop after exposure.
Causes of mesothelioma
Mesothelioma is almost always linked to asbestos exposure. When tiny asbestos fibers are inhaled or swallowed, they can become trapped in the body and cause irritation over time, leading to cancer.● Inhalation of asbestos fibers, especially in workplaces like construction, shipyards or insulation manufacturing
● Living with someone who works with asbestos, due to secondhand exposure from dust on clothing
● Environmental exposure in areas where asbestos occurs naturally
Risk factors for mesothelioma
Certain people are more likely to develop mesothelioma based on their work or environment. /p>
- Occupational exposure to asbestos (construction workers, plumbers, electricians and mechanics)
- Military service, especially Navy veterans, due to asbestos use on ships
- Living with someone exposed to asbestos (household contact)
- Older age – symptoms often appear later in life, typically after age 60
- Male gender – men are more frequently affected, likely due to occupational exposure
Symptoms of mesothelioma
Mesothelioma symptoms can be vague at first and often resemble other conditions. They depend on where the cancer is located.
Common signs of pleural mesothelioma (lung lining):
- Shortness of breath
- Chest pain or tightness
- Persistent cough
- Fatigue or weakness
- Unexplained weight loss
- Swelling or lumps under the skin on the chest
For peritoneal mesothelioma (abdominal lining):
- Abdominal pain or swelling
- Nausea
- Changes in bowel habits
- Unexplained weight loss
Diagnosing mesothelioma
Diagnosing mesothelioma usually requires imaging tests and a biopsy. Because it's rare and symptoms mimic other conditions, it often takes time to confirm.
- Chest X-ray or CT scan to look for fluid or tumors
- PET scan to detect cancer activity
- Blood tests for tumor markers (e.g., mesothelin)
- Biopsy (tissue sample) taken from the affected area for lab testing
- Thoracoscopy or laparoscopy (minimally invasive procedures to view the chest or abdomen)
Treatment of mesothelioma
Treatment options depend on the stage, location, and overall health of the patient. A team of specialists often works together to create a personalized care plan.
- Surgery to remove tumors (if detected early)
- Chemotherapy to shrink or slow the spread of cancer
- Radiation therapy for symptom relief or tumor control
- Immunotherapy to help the immune system target cancer cells
- Palliative care to manage symptoms and improve quality of life
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